OXIDOREDUCTASE. FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH R-2-HYDROXYGLUTARATE; OXIDOREDUCTASE, DIOXYGENASE, METAL-BINDING, TRANSCRIPTION, HELIX-LOOP-HELIX- ...
HIF induced gene transcription is inhibited by asparaginyl-hydroxylation as catalysed by FIH, in both normoxia and moderate hypoxia. bHLH: basic helix-loop- ...
Substance record SID 117636416 for (2R)-2-hydroxypentanedioic acid submitted by NCBI Structure.
Jul 20, 2021 · A similar role for hydroxylation is plausible in EGF domains, whereby hydroxylation leads to a more stable conformation that favors Ca2+ binding ...
SCOPe: Structural Classification of Proteins — extended database, and ASTRAL compendium for protein structure and sequence analysis.
Here we report that the cytoskeletal ankyrin family are substrates for FIH-catalyzed hydroxylations. We show that the ARD of ankyrinR is multiply hydroxylated ...
Missing: Triad| Aspartyl
-. Basic information · hypoxia-inducible factor-asparagine dioxygenase · : · carboxylic acid binding · ankyrin repeat binding · oxygen sensor activity ...
Jul 19, 2022 · Thus, 2OGDD involved in the regulation of transcription are likely to be of increasing interest in the study of epigenetic changes associated ...